Driving Change TOGETHER.
AOTI is committed to improving clinical outcomes while increasing access to care, improving quality of life and advancing health equity. Together with the American Diabetes Association, we have helped found the Amputation Prevention Alliance to address disparities in healthcare access and outcomes. We believe that everybody deserves access to clinically proven, effective therapies. We believe in saving limbs and saving lives.
Proven to deliver sustained wound healing
Supported by the highest level scientific studies, designed with integrity.
REAL WORLD EVIDENCE STUDY
RANDOMIZED CONTROLLED TRIAL
REDUCTION in Hospitalizations
REDUCTION in Amputations
REAL WORLD EVIDENCE STUDY
REDUCTION in Hospitalizations
REDUCTION in Amputations
RANDOMIZED CONTROLLED TRIAL
MORE LIKELY TO HEAL in 12 weeks*
LOWER RECURRENCE rate at 12 months*
The ONLY
therapy on the market proven to reduce amputations by 71%
The ONLY
therapy on the market proven to reduce amputations by 71%
Oxygen
Higher pressure delivery of O2 results in greater tissue diffusion, critical to restoring normal wound metabolism, resulting in more effective and durable healing.
Compression
Applies non-contact cyclical compression, reducing edema and mobilizing blood and lymphatic fluids, thus enhancing oxygen diffusion and neovascularization.
Humidification
A fine particulate mist helps create an ideal level of humidity for effective wound healing.
Oxygen
Higher pressure delivery results in greater tissue diffusion, upregulating wound metabolism, resulting in faster and more durable healing.
Compression
Non-contact, cyclical-compression helps to reduce edema and enhance peripheral vascular circulation and stimulate neovascularization.
Humidification
Assures an ideal wound healing environment for effective healing.

Thousands of patients have benefited from using TWO2 therapy at home.
Increasing Access. Improving Outcomes. Changing Lives.
Health Equity
Complementary
Durable Outcomes
We are passionate about providing solutions with outcomes that last. Our products have been proven to deliver sustained healing that saves limbs, helps improve patient quality of life and reduces healthcare costs.

Dr. Guberman
Podiatric Surgeon
“Mainstay of my practice…most superior system”

Cathy Smith
Nurse Practitioner
“It’s a Win/Win… All the way around”

Need more information?
Our dedicated customer service team is here to help.

Need more information?
Our dedicated customer service team is here to help.