CLINICAL EVIDENCE

TWO2 delivers the ability to close chronic non-healing and acute complex wounds, achieving more durable healing and providing significant clinical, quality of life and cost saving benefits.

Diabetic Foot Ulcers

REAL WORLD EVIDENCE STUDY

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REDUCTION in Hospitalizations

REAL WORLD EVIDENCE STUDY

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REDUCTION in Amputations

RANDOMIZED CONTROLLED TRIAL

Compared to standard of care alone

TWO2’s broad therapeutic benefits are supported by an extensive body of evidence and professional guidance

Featured Evidence

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All Clinical Evidence by Category

TWO2’s broad therapeutic benefits are supported by the highest-level evidence

Levels of Evidence

Pyramid Levels of Evidence

Scientific Clinical Advisory Board

Andrew Boulton1

Andrew Boulton – Chairman

MD, DSc (Hon), FACP, FICP, FRCP

President International Diabetes Federation (IDF). Chair EURADIA: Alliance for European Diabetes Research. Professor of Medicine at University of Manchester. Visiting Professor at University of Miami. Past-President European Association for the Study of Diabetes. Associate editor of Diabetes Care (ADA).
David Armstrong1

David Armstrong

DPM, PhD, MD

Professor of Surgery at the University of Southern California. Founder and co-chair of the American Limb Preservation Society (ALPS), International Diabetic Foot Conference (DFCON) & Southwestern Academic Limb Salvage Alliance (SALSA).
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Robert Frykberg

DPM, MPH, FRSM

Adj. Professor Midwestern University and Hon. Professor NUIG. Former Chair of the Foot Care Council of the American Diabetes Association (ADA) and former Chief of the Podiatry section at the Phoenix VAMC. Past President of the American College of Foot and Ankle Surgeons (ACFAS).
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Lee Rogers

DPM, RCPS, FFPM

Chief of Podiatry and Asc. Professor of Orthopedics at University of Texas Health Science Center (UTHSC). President of the American Board of Podiatric Medicine (ABPM). Asc. Editor of the Journal of the American Podiatric Medical Association.
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Anil Hingorani

MD

Vascular & Endovascular Surgeon at Vascular Institute of New York and New York University Langone Medical Center. Ast. Professor at Mount Sinai Medical Center and SUNY Downstate in Brooklyn. President of the Eastern Vascular Society.
Dane K Wukich

Dane K. Wukich

MD

Professor and Chair of the Department of Orthopedic Surgery at UT Southwestern. Medical Director of Orthopedic Surgery at UT Southwestern University Hospitals. Board member International Association of Diabetic Foot Surgeons (IADFS)
Christopher Attinger2

Christopher Attinger

MD

Professor at MedStar Georgetown University Hospital, Plastic & Reconstructive Surgery Department. Director of the Center for Wound Healing. Chairman of the Diabetic Limb Salvage Conference (DLS).
Loretta Vileikyte1

Loretta Vileikyte

MD, PhD

Senior Lecturer in Medicine at the University of Manchester and Research Associate Professor at the University of Miami. Academic Editor of Medicina.