Topical Wound Oxygen Therapy in Worsening Diabetic Foot Ulcers: A Case Report

Topical Wound Oxygen Therapy in Worsening Diabetic Foot Ulcers: A Case Report

Diabetic Foot Ulcers (DFUs) are a frequent complication of diabetes with attendant morbidity and mortality. There is some increasing evidence that supports the use of Topical Oxygen Therapy (TOT) in chronic DFUs when used in combination with standard wound care1. Specifically, Topical Wound Oxygen Therapy (TWO2) applies cyclically pressurized humidified oxygen within a single use extremity chamber connected to an oxygen concentrator2.

Synergistic Effects of Dehydrated Placental Allografts and Topical Wound Oxygen Therapy

Synergistic Effects of Dehydrated Placental Allografts and Topical Wound Oxygen Therapy

Wounds with bone exposure, in immunosuppressed patients after solid organ transplant, or post radiation, pose a significant challenge to heal. Bone exposure usually implies some form of osteomyelitis, which in the setting of immune suppression or radiation induced microvascular damage, usually translates to significant patient morbidity and prolonged healing time. We describe here our experience of healing two extremely challenging wounds, in two patients using a combination of two advanced modalities, designed to overcome these particular patient comorbidities.