Diabetic Foot Ulcers (DFUs) are a frequent complication of diabetes with attendant morbidity and mortality. There is some increasing evidence that supports the use of Topical Oxygen Therapy (TOT) in chronic DFUs when used in combination with standard wound care1. Specifically, Topical Wound Oxygen Therapy (TWO2) applies cyclically pressurized humidified oxygen within a single use extremity chamber connected to an oxygen concentrator2.
This Masterclass Guide is a concise overview aimed at exploring the use of Topical Wound Oxygen Therapy (TWO2) and incorporating this into your practice.
A summary of recent topical oxygen therapy evidence is presented, as well as the myths surrounding oxygen therapy. This guide is aimed at providing support for clinicians wishing to incorporate oxygen into their practice.
Wounds with bone exposure, in immunosuppressed patients after solid organ transplant, or post radiation, pose a significant challenge to heal. Bone exposure usually implies some form of osteomyelitis, which in the setting of immune suppression or radiation induced microvascular damage, usually translates to significant patient morbidity and prolonged healing time. We describe here our experience of healing two extremely challenging wounds, in two patients using a combination of two advanced modalities, designed to overcome these particular patient comorbidities.
Review Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers Robert G. Frykberg Diabetic Foot Consultants, LLC, Midwestern University, Glendale, AZ 85308, USA; rgfdpm@diabeticfoot.net Abstract: Oxygen is a critical component of many biological...