Synergistic Effects of Dehydrated Placental Allografts and Topical Wound Oxygen Therapy

Synergistic Effects of Dehydrated Placental Allografts and Topical Wound Oxygen Therapy

Wounds with bone exposure, in immunosuppressed patients after solid organ transplant, or post radiation, pose a significant challenge to heal. Bone exposure usually implies some form of osteomyelitis, which in the setting of immune suppression or radiation induced microvascular damage, usually translates to significant patient morbidity and prolonged healing time. We describe here our experience of healing two extremely challenging wounds, in two patients using a combination of two advanced modalities, designed to overcome these particular patient comorbidities.