24BY MATTHEW G. GAROUFALIS, DPM Disclaimer: Dr. Garoufalis is CMO of AOTI, Inc. Abstract Chronic wounds are a significant burden on healthcare systems and patients worldwide. Topical oxygen therapy, specifically intermittent cyclical pressurized topical wound oxygen...
Guidelines for the use of topical oxygen therapy in the treatment of hard-to-heal wounds based on a Delphi consensus A growing body of evidence supports the use of topical oxygen therapy (TOT) in the treatment of diabetic foot ulcers (DFUs). Anecdotal evidence...
REAL WORLD EVIDENCE STUDY Reduced Hospitalizations and Amputations in Patients with Diabetic Foot UlcersTreated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outcomes Jessica Izhakoff Yellin, Julia A. Gaebler, Frank F. Zhou, Timothy Niecko, Olivia...
RANDOMIZED CONTROLLED TRIAL A Multinational Multicenter, Randomized, Double-Blinded Placebo-Controlled Trial to Evaluate the Efficacy of Cyclical Topical Wound Oxygen Therapy (TWO2) in the Treatment of Chronic Diabetic Foot Ulcers: The TWO2 Study Robert G. Frykberg,1...
