FASTER and LASTING Healing with TWO2®
FASTER and LASTING Healing with TWO2®
As your partner in care, we are determined to give you the best quality treatment and help you back to living your life to the fullest.
Topical Wound Oxygen (TWO2®) is a clinically proven therapy for the treatment of chronic and difficult-to-heal wounds. The therapy is a safe, non-invasive treatment option that can be used in the comfort of your own home.
Why Choose TWO2® therapy?
A Unique 3-in-1 Therapy
All wounds need oxygen to heal. Chronic wounds can become hypoxic, or low in oxygen. The Extremity Chamber (or “Boot”) gives the wound the oxygen it needs to heal. At the same time, compression from the Boot improves blood flow to help reduce swelling (edema). Lastly, humidification ensures an ideal wound healing environment.
Convenient & Easy-to-use
TWO2 therapy is designed with the patient in mind. You can use the therapy in your home while watching TV or reading a book. At the start of therapy, an AOTI representative will drop the equipment off at your home and teach you how to begin a therapy session. Our Patient Guide walks you through each of the steps in case you want a reminder after the representative leaves your home. If you have any questions or concerns, our representatives and customer service teams are just a phone call away.
Compatible with dressings and TCCs
You can often wear your usual dressings and/or total contact casts (TCCs) underneath the Extremity Chamber (Boot). Your doctor will tell you if your dressings are compatible with TWO2 therapy or if they must be removed before therapy.
Clinically Proven
- Faster healing*1,2
- Reduces wound recurrence rates1,2
- Prevents amputations and hospitalizations3
- Reduces pain2
*Compared to Standard of Care. Standard of Care for DFU includes offloading, dressing that provides a moist wound healing environment, exudate management and debridement of necrotic tissue. Standard of Care for VLU includes multi-layer gradient compression dressings, dressings that provide a moist wound healing environment, exudate management and debridement of necrotic tissue.
1. 6X More likely to heal DFUs in 12 weeks, 6X Less likely DFUs recur at 12 months:
Frykberg R, Franks P, et al. A multinational, multicenter, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy of cyclical Topical Wound Oxygen (TWO
2. 2X Faster VLU healing, 87% Lower VLU recurrence rate at 36 months, Pain score dropped from 8 to 3 in 13 days:
Tawfick WA, Sultan, S. Technical and Clinical Outcome of Topical Wound Oxygen in Comparison to Conventional Compression Dressings in the Management of Refractory Nonhealing Venous Ulcers. Vascular and Endovascular Surgery, 2012.
3. 88% Reduction in hospitalizations, 71% Reduction in amputations:
Yellin J, et al. Reduced Hospitalizations and Amputations in Patients with Diabetic Foot Ulcers Treated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outcomes. Advances in Wound Care, 2021.
How Do I Get Started?
Talk to your doctor to see if TWO2 is right for you. Before finalizing your treatment plan, you and your provider should check your health insurance to make sure the cost will be covered.
How Do I Get Started?
Talk to your doctor to see if TWO2 is right for you. Before finalizing your treatment plan, you and your provider should check your health insurance to make sure the cost will be covered.
Getting Started & What to Expect
Before starting the therapy, you should use the bathroom, eat or grab a snack, and gather anything you want to have near you during therapy—such as a TV remote, a book, your phone, and a glass of water.
Watch the setup video
PATIENT Testimonials
Need more information?
Our dedicated customer service team is here to help.
Need more information?
Our dedicated customer service team is here to help.