More durable wound healing with proven long-term reductions in DFU recurrence, hospitalizations, and amputations, resulting in reductions to total cost of care

REAL WORLD EVIDENCE STUDY

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REDUCTION in Hospitalizations

REAL WORLD EVIDENCE STUDY

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REDUCTION in Amputations

RANDOMIZED CONTROLLED TRIAL

Compared to standard of care alone

More durable wound healing with proven long-term reductions in DFU recurrence, hospitalizations, and amputations, resulting in reductions to total cost of care

REAL WORLD EVIDENCE STUDY

88 reduction homepage 01

REDUCTION in Hospitalizations

REAL WORLD EVIDENCE STUDY

71 reduction homepage 01

REDUCTION in Amputations

RANDOMIZED CONTROLLED TRIAL

Compared to standard of care alone

The secret to durable healing is multi-modality TWO2 therapy

The secret to durable healing is multi-modality TWO2 therapy

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Oxygen

TWO2 delivers high pressure O2 which results in greater tissue diffusion and restoration of normal wound metabolism, critical to restoring normal wound metabolism, allowing for more effective and durable healing.

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Compression

TWO2 applies non-contact cyclical compression which reduces edema and mobilizes blood and lymphatic fluids, enhancing oxygen diffusion and neovascularization.

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Humidification

TWO2 supplies a fine particulate mist which helps to create the ideal level of humidity for effective wound healing.

Driving Change TOGETHER

Amputation Prevention Alliance

The American Diabetes Association awarded Topical Oxygen Therapy an A-grade adjunctive treatment recommendation for diabetic foot ulcers.

ADA Diabetes Care Supplement SOC25 OCT NEW

Thousands of patients have benefited from using Topical Wound Oxygen (TWO2) therapy at home

Thousands of patients have benefited from using Topical Wound Oxygen (TWO2) therapy at home

Acclaimed by Clinicians

Dr.-Guberman

Dr. Guberman

Podiatric Surgeon

“Mainstay of my practice…most superior system”

Cathy Smith

Dr. Dua

Vascular Surgeon

“Being able to have the patient in the home, get[ting] their therapy is really the crux of delivery and access to care.”

Cathy Smith

Dr. Dexter

Vascular Surgeon

“TWO2 allows me to provide therapy to someone at home.”

Extremity Chamber

What's Next?

CLINICIANS

Get in touch for a product demo.

PATIENTS

Talk to your doctor to see if an AOTI solution is right for you.

The Only Topical Wound Oxygen Therapy Proven to Durably Heal Acute and Chronic Wounds

Backed by an exceptional level of evidence, TWO2 is clinically proven to reduce costs, prevent hospitalizations, and avoid amputations, helping your patient heal and stay healed.